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March 1925

THE LOCALIZATION OF A LESION IN THE BRAIN BY DIFFERENTIAL STAINING OF BLOOD SMEARS: PRELIMINARY REPORT

Author Affiliations

SENDAI, JAPAN
From the Pediatric Department of the Medical College of the Tohoku Imperial University.

Am J Dis Child. 1925;29(3):313-317. doi:10.1001/archpedi.1925.04120270014002
Abstract

In the past, there has been no method of localizing lesions in the brain except by a careful mental and physical examination of the patient. No purely laboratory finding which might lead to such localization has been described. Changes in the blood, characteristic of injuries to certain parts of the brain, have not been recorded. Stern1 argued against the possibility of such characteristics by pointing out that there was no relation between the degree of change in the blood picture and the degree of cerebral damage. Moreover, even if it were possible to produce a definite change in the blood picture (such as an eosinophilia) by experimental injury of a certain part of the brain, it would by no means follow that a patient presenting such a blood picture must necessarily have a lesion of this part of the brain.

In another paper, published in this issue, Yoshimatsu and

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