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June 1925

THE DUODENAL CONTENTS OF INFANTS IN HEALTH, AND DURING AND FOLLOWING DIARRHEA: PRELIMINARY REPORT

Author Affiliations

BALTIMORE
From the Department of Pediatrics, Johns Hopkins University and the Harriet Lane Home, Johns Hopkins Hospital.

Am J Dis Child. 1925;29(6):743-756. doi:10.1001/archpedi.1925.04120300017002
Abstract

In this study of the relation between the results of analyses of duodenal contents and the state of digestion, I have determined the hydrogen ion concentration and the amylase and the trypsin activity, and have made aerobic cultures of 50 specimens of duodenal contents obtained from twenty-five infants. Six of these infants were normal, eight were convalescent from diarrhea (one of these died as a result of pneumonia), six died of diarrhea and five succumbed to bacillary dysentery (Flexner). By the term diarrhea, I refer to all types of infantile diarrhea, except bacillary dysentery. Diarrhea and dysentery can be readily distinguished on clinical as well as on bacteriologic grounds.1 The patients who died as a result of diarrhea had been losing weight and had had frequent loose, watery stools. Those who were convalescent from diarrhea were gaining weight slowly and had from two to eight semiformed stools daily.

METHODS 

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