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July 1925

RELAPSES IN MEASLES: REPORT OF THREE CASES, ONE TREATED WITH CONVALESCENT MEASLES SERUM

Author Affiliations

NEW YORK
From the Department of Pediatrics, University and Bellevue Hospital Medical College, and the Willard Parker Hospital.

Am J Dis Child. 1925;30(1):55-56. doi:10.1001/archpedi.1925.01920130061010
Abstract

One attack of measles almost always, but not invariably, confers immunity. Although second attacks undoubtedly occur, they are very rare. In their extensive experiences, Loos,1 Widowitz,2 and Panum3 did not observe a single instance in over 7,000 cases. A sufficient number of definitely authenticated cases of second attacks has been reported, however, to prove the occasional occurrence.

ETIOLOGY  Second attacks of measles are classified as either recurrent or relapsing. In relapses, the disease recurs with all the classical signs and symptoms in from one to four weeks after the attack is apparently over, but while the original infection is still present in the system. In recurrent attacks, the disease recurs months or years later.

REVIEW OF THE LITERATURE  Maizeles,4 in an extensive review of the literature, collected 103 cases of recurrent measles. Ruhräh,5 Barthez and Sannée,6 Feer,7 Kerley,8 and Lewy9 have

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