In a series of 100 cases of congenital syphilis in the University Clinic during a period of three and a half years, two children have presented themselves with gummatous osteoperiostitis of the skull, in addition to other lesions of congenital syphilis. The interest in these cases lies in the rarity of involvement of the skull in the gummatous process, and in the scarcity of reports of this condition.
Case 1.—H. Z., a girl, Polish, aged 8 years, was admitted to the New Haven Hospital; Feb. 17, 1919, with the complaint of "sores on the legs."Family History.—The patient's father died at the age of 37, following an operation on the jaw. He was said to have been tuberculous. The mother is living and well. There are two sisters and three brothers living and well. One child died at 2 weeks and one at 6 months of age.
ETHEL C. DUNHAM. GUMMATOUS OSTEOPERIOSTITIS OF THE SKULL IN CONGENITAL SYPHILISREPORT OF TWO CASES. Am J Dis Child. 1925;30(5):690–699. doi:10.1001/archpedi.1925.01920170094010