The function of the pancreas has been the subject of investigation by pediatricians on three occasions only. When it first was recognized that the physiology of an adult is not in every respect similar to that of the infant, and when Czerny's classical saying became widely known—"An infant is not a miniature adult," Zweifel, Jakubowitch,1 Moro,2 Ibrahim,3 Hammarsten, etc., and later Hess,4 made researches on the physiologic function of the infant's pancreas. We then became aware that the pancreas of the 6 month fetus contains active ferments, and that the pancreatic ferment production of the infant is greater than that of the adult.At this time, nutritional disturbances were called "digestive disturbances." It was logical that after recognizing the physiologic function one should raise the question whether the so-called "digestive disturbances" are not caused by decrease of the digestive ferments. The investigations of
LUKACS T. TRYPSIN SECRETION OF INFANTSWITH SPECIAL REFERENCE TO RICKETS. Am J Dis Child. 1926;31(2):235–240. doi:10.1001/archpedi.1926.04130020087009
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