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Progress in Pediatrics
March 1926

ACIDIFIED MILKS: WITH SPECIAL CONSIDERATION OF THE INDICATIONS AND LIMITATIONS TO THEIR USE

Author Affiliations

SAN FRANCISCO
From the Division of Pediatrics, Stanford University Medical School.

Am J Dis Child. 1926;31(3):395-409. doi:10.1001/archpedi.1926.04130030082010
Abstract

The recent literature on acidified milk in infant feeding has been repeatedly1 reviewed in this journal, and therefore need not be summarized again.

The modification of cow's milk by the addition of acid is based on the high content of buffer substances in cow's milk, the resistance of which must be broken down before gastric digestion can proceed normally. The buffering property of milk was recognized first by Leo2 in 1888, and was soon thereafter studied by Escherich3 (1889), by Heubner4 (1891), and by Müller5 ( 1892). Müller found that it was two to three times as great in cow's milk as in human milk These workers employed the method of titrating with hydrochloric acid, using congo red (PH range from 3 to 5) as an indicator. It was not until 1914 that the buffer curve of milk was charted according to hydrogen ion concentration.

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