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September 1926


Author Affiliations

From the Division of Contagious Diseases, Cleveland City Hospital, and from the Department of Pediatrics, Western Reserve University.

Am J Dis Child. 1926;32(3):401-406. doi:10.1001/archpedi.1926.04130090078012

Von Torday,1 Weaver,2 and Zingher,3 have reviewed the literature on the use of convalescent measles serum in the prophylaxis of measles. The number of susceptible subjects injected, and the results, are summarized in table 1.

Tunnicliff and Hoyne4 injected goats with the green producing diplococcus suggested by the former author as being the cause of measles, and used the serum of this animal in the same way as others use measles convalescent serum.

METHOD OF EXPERIMENT  From Jan. 1, 1923, to April 1, 1925, 190 susceptible persons have been injected intramuscularly with measles convalescent serum as a prophylactic measure, no serum being given when the history of exposure was more than six days. The serum obtained was from donors eight days after the rash began to disappear; was inactivated one hour at 56 C., sealed and stored on ice, no preservative being added. In some of

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