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January 1927

CALCIUM METABOLISM STUDIESA. THE RAISING OF SERUM CALCIUM BY TOPICAL APPLICATIONS OF RAW AND ACTIVATED COD LIVER OIL B. DISTURBANCES ASSOCIATED WITH THE ACTIVE DENTAL CARIES OF CHILDHOOD AND PREGNANCY

Am J Dis Child. 1927;33(1):78-95. doi:10.1001/archpedi.1927.04130130085006
Abstract

That sunshine and cod liver oil will markedly affect calcium metabolism is altogether likely. The processes by which these effects are produced are but little understood. The studies presented here are part of a series being made to obtain data to throw light on the nature of the forces at work, and the mechanisms involved in the utilization of calcium by the body with special considerations of disturbances in calcium metabolism, particularly those which relate to tooth and bone formation, and degenerative changes in those structures after their development.

It has been demonstrated by many workers, especially by Alfred F. Hess,1 Mildred Weinstock2 and H. Steenbock,3 that when animals are placed on a diet deficient in either phosphorus or calcium in the absence of sunlight, disturbances of the hard structures tend to appear, and that these may be prevented or corrected in large part by the addition

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