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January 1927

SERUM TEST (TUBERCUMET) FOR ACTIVE TUBERCULOSIS: REPORT OF RESULTS ON ONE HUNDRED PATIENTS

Am J Dis Child. 1927;33(1):105-115. doi:10.1001/archpedi.1927.04130130112008
Abstract

Since the Wassermann test was devised and has proved of such valuable aid in the diagnosis of syphilis, attempts have been made to devise a similar test for the diagnosis of active tuberculosis.

The complement-fixation test was thought for a time to fulfil the requirements of a test for activity. It has been largely dropped, as it was found to be positive in nontuberculous persons, negative in tuberculous persons and either positive or negative in those nonactively tuberculous. At present, the flocculation test belonging to the precipitin group of reactions is receiving most attention. Some observers claim that it is a specific test for active tuberculosis; others find it negative in many patients actively tuberculous and positive in those nonactively tuberculous. The results of a greater number of observers will be necessary to prove its true value.

In the summer of 1925, Eli Lilly and Company advertised by literature and

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