This rare condition of the hands and feet, although in the past studied chiefly by dermatologists, should interest pediatricians as well, on account of its hereditary nature and its tendency to appear in early life. Then, too, it must be considered in differential diagnosis with a number of cutaneous disorders of childhood.
First described by Krost,1 in 1880, and by Unna.1 in 1883, the hereditary character of this form of keratodermia was emphasized by the earliest authors. Vörner recorded its existence in four generations of one family, sixteen out of forty members being affected. Cases have been reported from time to time in Europe, North and South America and Japan. The high incidence of the disease among the natives of the small island of Meleda in the Adriatic Sea off the coast of Dalmatia led early observers in this locality to attach to it the name of mal
OLMSTED HC. KERATODERMIA PALMARIS ET PLANTARIS CONGENITALIS: REPORT OF A CASE SHOWING ASSOCIATED LESIONS OF UNUSUAL LOCATION. Am J Dis Child. 1927;33(5):757–764. doi:10.1001/archpedi.1927.04130170055008
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