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Book Reviews
September 1927


Am J Dis Child. 1927;34(3):518. doi:10.1001/archpedi.1927.04130210193020

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The author proposes a new procedure for immunization. It is based on the experimental work of Abderhalden, who found that antitoxins produced in the animal organism have the nature and characteristics of ferments; hence the name "Abwehrfermente," which was coined by him. He developed the theory that the animal organism utilized ferments in this manner as a defense mechanism.

On the basis of Abderhalden's theories, the author conceived the idea of introducing parenterally foreign proteins combined with the toxin of the disease in question, in the hope that this combined stimulus would produce the antibody ferment. These ferments, in turn, would break down the toxic protein substances and in this manner neutralize the harmful effect of pathogenic organisms.

Horse serum and ox serum were used as foreign protein, and the urine of the patient affected with the specific infectious disease was used as the vehicle containing the toxin of such

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