Though clinical methods at present available for the study of the function of the kidney are not entirely satisfactory, one does, by a combination of certain tests, obtain a fairly reliable index of the renal efficiency of adults. The selection of tests from the many available depends chiefly on clinical ideas of lesions of the kidney. It may be said, generally, that there are three types of tests: (a) those detecting and measuring disturbances of the excretion of nitrogen, (b) those showing disturbances in the excretion of salt and of water, and (c) those indicating the efficiency of the kidneys in the part they play in regulating body neutrality. In the present communication we are concerned chiefly with the first type of test, namely, that which indicates the efficiency of the kidneys in the excretion of nitrogen.
The general principle underlying the various tests in use is that when the
RABINOWITCH IM, BREITMAN R. THE ESTIMATION OF RENAL EFFICIENCY OF CHILDREN: STUDIES ON THE EXCRETION OF NITROGEN. Am J Dis Child. 1927;34(6):1000–1006. doi:10.1001/archpedi.1927.04130240079011
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