It is evident from the numerous inquiries that are received at the Willard Parker Hospital that the true value of scarlet fever antitoxin is not generally known; with this in view, the following observations are presented.
The series presented consists of 465 consecutive and unselected cases, in which 250 of the patients did not receive antitoxin. I feel, therefore, that the real value of the antitoxin can be obtained.
All patients with scarlet fever who were admitted to the hospital did not receive antitoxin, for it was apparent that in the moderately severe and in the mild cases the patients did not show sufficient toxemia to warrant the treatment. Furthermore, the serum rash that may appear often causes more subjective symptoms than the disease per se. Therefore, it was decided that the temperature and the clinical observations should govern the administration of the antitoxin. As a rule, patients who had
R. CANNON ELEY. SCARLET FEVER ANTITOXINREPORT OF FOUR HUNDRED AND SIXTY-FIVE CASES. Am J Dis Child. 1928;35(1):14–17. doi:10.1001/archpedi.1928.01920190021003