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August 1928


Author Affiliations

From the laboratories of the Subdepartment of Pediatrics, University of Toronto, the Hospital for Sick Children, and the wards of the Hospital for Sick Children.

Am J Dis Child. 1928;36(2):298-309. doi:10.1001/archpedi.1928.01920260106006

During the past three years, more than 400 determinations of blood fat have been made in eighty patients with diabetes attending the Hospital for Sick Children, Toronto. Bloor's1 nephelometric method was used, and the determinations were made on the plasma. Ample figures for the normal blood fats of children have been furnished in the literature by Marriott and Sisson2 and by Cowie and Hoag.3 The former workers give 590 mg. of fat per hundred cubic centimeters of blood as the normal, and the latter, 700 mg. These figures vary little from those obtained by Bloor in normal adults.

Since the days when bleeding was in vogue as a universal therapeutic procedure, milkiness of the serum has been noted in persons with diabetes, and for more than a hundred years such milkiness has been attributed to increased fat content. Distinct turbidity of the blood plasma was noted in