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March 1929


Author Affiliations

From the Municipal Contagious Disease Hospital, Department of Health, Chicago.

Am J Dis Child. 1929;37(3):553-558. doi:10.1001/archpedi.1929.01930030095009

Four years have elapsed since the introduction of concentrated scarlet fever antitoxin prepared according to the methods of the Dicks and of Dochez. During that time numerous reports have been published regarding the value of scarlet fever antitoxin. Some observers have declared the serum a "specific" in the treatment of scarlet fever and recommend giving the antitoxin in every case.1 Some have questioned the value of the serum in the milder types,2 while others have believed the serum had little, if any, therapeutic value.3

In this study of 492 cases of scarlet fever, an attempt has been made to determine in what cases the use of scarlet fever antitoxin is indicated, and what results may be looked for in regard to the course of the disease and the prevention of complications.

This report includes all the patients admitted to the Municipal Contagious Disease Hospital within a period