In a recent review of the literature I found few attempts to correlate the clinical and pathologic changes observed in premature infants. In the period covered by this study, 102 infants were under observation in the Premature Station of the Sarah Morris Hospital. The care and feeding of this same group of premature infants was discussed by Hess and Chamberlain. Fifty-four infants of this group were discharged from the station in good condition; forty-eight died, and a complete necropsy was performed on thirty-six. In these, the pathologic processes found were studied with the clinical course as a background in an effort to evaluate the symptoms which had been in evidence. The histories and observations of the infants who died were reviewed from the clinical and pathologic point of view in an attempt to use the information thus gained in furthering the survey of the group that lived, more particularly with