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Case Reports
August 1929

THE ANTIDIURETIC EFFECT OF SOLUTION OF PITUITARY DROPPED INTRANASALLY IN A CASE OF DIABETES INSIPIDUS

Am J Dis Child. 1929;38(2):342-347. doi:10.1001/archpedi.1929.01930080118013
Abstract

A. E., a girl, aged 9 years, first appeared in the clinic in April, 1927, with the complaint of increased thirst, frequency of urination and marked malnutrition. The past and family histories were essentially unimportant. The present illness began in October, 1925, at which time she had to be removed from school because of polydipsia and polyuria.

Examination.—Physical examination showed an extremely malnourished and markedly underweight child (fig. 1). The weight was 38 pounds (17.2 Kg.). She seemed rather dull and apathetic, and did not take much interest in her surroundings. The skin was dry and loose and the bladder was distended to the umbilicus; otherwise, the results of the physical examination were negative. The results of the special examinations, as of the fundus and visual fields, and the results of laboratory examinations, including the chemical analysis of the blood, the Wassermann test of the blood and tests of

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