History.—J. S., a boy of Russian Jewish parentage, aged 11 years, was brought to the outpatient department of the New York Neurological Institute, March 15, 1926, with the complaint of blindness. He said that he did not remember ever having seen with his right eye. At the age of 6, when he was first sent to a New York public school, his defective vision was called to the attention of his parents; at this time, vision in the left eye was also apparently failing. He continued in the public school for normal children for another two years in spite of his defective vision, but at 8 years of age was unable to continue because of complete failure of vision and was transferred to the school for the blind. (He was attending this school when he was last seen.) In addition to the blindness, a secondary complaint was enlargement and