GAUCHER'S DISEASE: A REVIEW OF THE LITERATURE AND REPORT OF A CASE DIAGNOSED FROM SECTION OF AN INGUINAL LYMPH GLAND

In 1882 Ernest Gaucher¹ described a form of splenic anemia which he termed "primary idiopathic hypertrophy of the spleen," and which today bears his name. It was not until thirteen years later that Collier² in England, and Picou and Ramond³ in France, described the next cases. In 1900, Bovaird⁴ reported the first American case. In 1904, Brill and Mandlebaum⁵ added the next case to the literature, in which they described for the first time the occurrence of the large characteristic cells in the bone-marrow, and also added much to the knowledge of the pathology of this disease. Schlagenhaufer,⁶ in 1907, reported the first case in the German literature. Since then, cases have been reported at regular intervals and with increased frequency. Mandlebaum,⁷ in 1919. stated that up to date there were twenty-one authentic cases on record. Ludwig Pick,⁸ in 1926, collected thirty-nine