In a series of cases of acute nephritis in children studied on the Children's Medical Division at Bellevue Hospital in the past seven years, we have had the opportunity to observe the manifestations of this disease and to note its progress. Though we speak of it as a disease entity involving one organ, the kidney, it must be remembered that at least two distinct types of acute renal involvement may be present, depending on whether glomeruli or tubules are predominantly involved. The classification of acute nephritis on a purely clinical basis affords no great difficulty if one remains aware that no system of classification is absolute. A pure acute glomerular nephritis without tubular damage may be postulated, but it probably exists rarely, if at all. Capon1 said:
It is a truism to state that when a child's kidneys become inflamed it is rare to find on histological examination that
LYTTLE JD, ROSENBERG L. THE PROGNOSIS OF ACUTE NEPHRITIS IN CHILDHOOD. Am J Dis Child. 1929;38(5):1052–1063. doi:10.1001/archpedi.1929.01930110151019
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