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January 1930


Author Affiliations

From the Babies' Hospital and the Pediatric Department of Columbia University College of Physicians and Surgeons.

Am J Dis Child. 1930;39(1):115-130. doi:10.1001/archpedi.1930.01930130127014

Five of the ten patients on whom splenectomy has been performed at the Babies' Hospital show a sufficient number of points in common to warrant grouping them as examples of a familial, hemolytic type of infantile anemia which is not cured by splenectomy. The postoperative reaction is a form of marrow stimulation expressed in large numbers of normoblasts in the circulating blood. Four of the five children died. The brother of one of the patients and three others with a similar blood picture, three of whom were not operated on, have been added to the group. Thus are included two brothers in whose family three other cases were said to have occurred, a brother and sister, a boy whose family history shows one similar case and four girls without a familial history. Six of the families were Italian, and one was Greek. All of the nine children were born in

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