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March 1930


Author Affiliations

From the Department of Pediatrics, Washington University School of Medicine, and the St. Louis Children's Hospital.

Am J Dis Child. 1930;39(3):517-528. doi:10.1001/archpedi.1930.01930150049006

In recent years, considerable attention has been paid to a peculiar combination of chronic renal disease and deformity of the bones, known as "renal infantilism," renal dwarfism" or "renal rickets." Shipley and his co-workers and1 Lathrop,2 Hunt,3 Parsons4 and Duken5 have reviewed the literature on this subject and contributed additional case reports.

Parsons, who has made the most extensive chemical study of this condition, has stated that the bone deformities are those of true low calcium rickets, which, according to the x-ray picture, should be classified into three types: (a) atrophic type, (b) florid type and (c) "woolly" type. The decrease of the calcium level of the blood may be absolute, as in one case reported by Parsons4 in which it was diminished to 3.95 mg. per hundred cubic centimeters, or only relative; that is, the calcium value is normal but low as compared