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March 1930

HIGH PHOSPHORUS CONCENTRATIONS IN INFANTILE TETANY: A REPORT OF TWENTY CASES, WITH A REVIEW OF THE LITERATURE

Author Affiliations

NEW YORK
From the Department of Pediatrics, Cornell University Medical College and the New York Nursery and Child's Hospital.

Am J Dis Child. 1930;39(3):536-543. doi:10.1001/archpedi.1930.01930150068008
Abstract

Infantile tetany has been recognized as a clinical entity for many years, but Howland and Marriott1 in 1918 were the first to describe its characteristic blood chemistry. They showed that the calcium content of the serum was greatly reduced in the active stages of tetany. Kramer, Tisdall and Howland2 found that electrical reactions typical of tetany (the cathodal opening contraction less than 5 milliamperes and the anodal opening contraction less than the anodal closing contraction) were present when the calcium content of the serum was less than 7.5 mg. per hundred cubic centimeters. Little attention has been paid to the inorganic phosphorus content of the serum in tetany, as that has generally been reported to be at or slightly below the normal level. Thus in 1921 Kramer, Tisdall and Howland2 reported normal values in seven cases of infantile tetany. Hess3 and his co-workers in 1923 determined

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