While the Kahn reaction has been extensively studied in adults with syphilis, it has not been investigated on a large scale in children. There are several reasons why the reaction should be especially studied in this group of cases. Many infectious diseases are most common in childhood. Furthermore, until recently, laboratory tests for syphilis have not been as dependable in detecting the congenital state of this disease as the acquired state
An opportunity was afforded in the department of pediatrics and infectious diseases to study the specificity and sensitivity of the Kahn reaction. It was desired to determine to what extent the various clinical conditions found in juvenile medical practice will affect the specificity of this reaction. It will be recalled that many authors are of the opinion that some of the febrile diseases will bring about false positive Wassermann reactions. In the case of the Kahn reaction, recent studies
MANACE G. EVALUATION OF THE KAHN REACTION IN CHILDREN. Am J Dis Child. 1930;40(1):63–69. doi:10.1001/archpedi.1930.01940010074006
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