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October 1930

CEREBROSPINAL FLUID OF PREMATURE INFANTS: RESULTS OF A SERIES OF SPINAL PUNCTURES IN ONE HUNDRED AND SEVENTY CASES, WITH SPECIAL REFERENCE TO THE ORIGIN OF PHYSIOLOGIC XANTHOCHROMIA OF THE NEW-BORN INFANT

Author Affiliations

ROCHESTER, N. Y.
From the Leon Klein Fund, the Premature Infant Station of the Sarah Morris Hospital for Children and the Nelson Morris Institute for Medical Research of the Michael Reese Hospital, Chicago.

Am J Dis Child. 1930;40(4):741-752. doi:10.1001/archpedi.1930.01940040038004
Abstract

Some time ago the results of a series of spinal punctures on 100 premature infants were published and discussed with particular reference to intracranial hemorrhage and pigmentation of the cerebrospinal fluid.1 Since then the series has been increased to 170 infants. In general, though there have been but few changes in the conclusions advanced in the first paper, the conditions observed in the second series of 70 infants, together with a theory that has been developed in the course of the work to explain physiologic xanthochromia of the new-born infant, are sufficiently interesting to warrant publication. In the discussion to follow, the term "meningeal" hemorrhage will be used instead of "cerebral" or "intracranial," as the former term more accurately designates the pathologic condition under consideration.

TECHNIC  The technic previously described for lumbar puncture in premature infants has continued satisfactory. In brief, this consists in using a small hypodermic needle (no.

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