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Case Reports
November 1931


Author Affiliations

From the Pediatric Service of the Jewish Hospital of Brooklyn, Dr. Benjamin Kramer, pediatrician-in-chief.

Am J Dis Child. 1931;42(5):1160-1170. doi:10.1001/archpedi.1931.01940180110018

Purpura hemorrhagica is a condition associated with marked diminution in the blood platelets, spontaneous bleeding from the mucous membranes and purpuric lesions of the skin. It may occur in a primary or idiopathic form (called essential thrombopenia), or as a secondary manifestation in pernicious anemia, lymphatic leukemia, diphtheria and tuberculosis.

Tuberculosis, among other diseases, has been considered as etiologically related to purpura. In 1827, Rayner1 first mentioned the relationship of purpura to tuberculosis. Both Dieulafoy2 and Strumpell3 named pulmonary tuberculosis as one of the causative factors in symptomatic purpura. Cruice4 concluded that there are numerous cases of purpura in the course of extrapulmonary tuberculosis (tuberculous adenitis, peritonitis and meningitis). In an intensive study, Bensaude and Rivet5 reported cases of purpura hemorrhagica in acute and chronic pulmonary and extrapulmonary tuberculosis. According to these authors, purpura occurring in the course of chronic pulmonary tuberculosis is much more

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