The statement that knowledge relating to this disease condition is in an unsatisfactory state will be accepted without argument. Many authors feel that von Jaksch did not describe this disease, and that the term "von Jaksch's anemia" includes a miscellaneous group of diseases. As described by Cooley1 this disease now has a well established and cleancut clinical picture, with careful reports from a number of clinics in this country. Cooley2 considered the condition as essentially due to hemolysis, and related the bone changes to the extreme hyperplasia of the red marrow. Wollstein and Kreidel3 referred to the disease as a familial hemolytic anemia. It is fair to state that the study of anatomic material has not been as complete and satisfactory as the clinical reports. For this reason it seemed wise to report in detail the gross and histologic observations in the two cases herein reported.
WHIPPLE GH, BRADFORD WL. RACIAL OR FAMILIAL ANEMIA OF CHILDREN: ASSOCIATED WITH FUNDAMENTAL DISTURBANCES OF BONE AND PIGMENT METABOLISM (COOLEY-VON JAKSCH). Am J Dis Child. 1932;44(2):336–365. doi:10.1001/archpedi.1932.01950090074009
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