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Case Reports
October 1932

STAPHYLOCOCCUS AUREUS MENINGITISTREATMENT WITH SPECIFIC BACTERIOPHAGE

Am J Dis Child. 1932;44(4):813-822. doi:10.1001/archpedi.1932.01950110115011
Abstract

The septic meningitides, including infections of the meninges due to various forms of staphylococci, streptococci, pneumococci and influenza bacilli, are, unfortunately, discussed in the literature more frequently as a group than in separate categories based on the causal organisms.

Griffith1 considered these cases in the new-born as complications of umbilical infection, and in older children as secondary to otitis media, empyema, erysipelas and joint infection and usually associated with sepsis elsewhere in the body. As to termination, he stated that these cases run a "short course and the prognosis is almost entirely unfavorable." Treatment for the streptococcic and pneumococcic varieties by intraspinal serum injection was mentioned; frequent drainage of the canal by lumbar puncture and intraspinal injections of methenamine were suggested in other types.

Porter and Carter2 stated that "in staphylococcic meningitis, treatment is essentially symptomatic and invariably useless." Holt3 too gave the treatment for this form

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