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Book Reviews
February 1933

A Suggestion for an Experimental Attempt at Local Immunization in Poliomyelitis Through Irradiation of the Portals of Entry.

Am J Dis Child. 1933;45(2):455. doi:10.1001/archpedi.1933.01950150228019

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The author states that he has obtained rapid local immunization in the treatment of large numbers of patients with focal infection by focal irradiation with ultraviolet rays. He suggests the possibility that if local immunity could be increased sufficiently, the poliomyelitis virus could be destroyed at its portal of entry into the body and prevented from reaching the nervous system. To test this theory, a series of experiments on monkeys is suggested, such as the administration of poliomyelitis virus followed by exposure to ultraviolet rays.

The author apparently has profound confidence in the ability of ultraviolet rays to arrest infectious processes, even deep infections, when the rays are applied to the skin. The arguments for means of increasing local resistance are unconvincing.

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