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Other Articles
July 1933


Author Affiliations

Fellows in Pediatrics, the Mayo Foundation ROCHESTER, MINN.

Am J Dis Child. 1933;46(1):24-29. doi:10.1001/archpedi.1933.01960010034004

The urine of persons who are on a general diet invariably contains nitrates. Mitchell, Shonle and Grindley1 stated that the average concentration of nitrates calculated as potassium nitrate in the urine of normal persons is from 10 to 20 mg. for each 100 cc., and that occasionally it may be as high as 30 or 40 mg. for each 100 cc. Mayerhofer2 quoted Röhman, and also Weyl and Citron, as stating that 4.25 mg. in each 100 cc. is the usual amount present. Because most foodstuffs, but particularly vegetables, contain nitrates, it was supposed that the nitrates in the urine were derived exclusively from the food. According to Grindley and Mitchell,3 Röhman was unable to recover nitrate from the urine of dogs fed on meat or from rabbits fed on milk and wheat bread, and his results were confirmed by Weyl and Citron. Experiments in which diets