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January 1934

SO-CALLED THYMIC HYPERPLASIA: IV. A FOLLOW-UP STUDY OF THIRTY CASES

Author Affiliations

DETROIT
From the Allergy Clinic, Children's Hospital of Michigan.

Am J Dis Child. 1934;47(1):34-40. doi:10.1001/archpedi.1934.01960080043004
Abstract

The purpose of this paper is to set forth additional evidence for data obtained in an investigation1 on the pathology of so-called thymic death. In this study it was found that edema of the lungs which cannot be explained on the basis of any cardiac or renal disease, and which is suggestive of an allergic origin, is a constant finding in so-called thymic death. Therefore it seemed to be of interest to examine a number of patients with a previous roentgen diagnosis of thymic hypertrophy for the purpose of discovering any possible association with allergy.

Recent literature on the thymic problem is full of controversies. The questions mainly under discussion concern the following points: What constitutes a normal, and what a large, thymus?2 Is death produced by obstruction of the trachea?3 What is the function of the thymus gland? Is one justified in giving roentgen treatment over

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