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April 1934

Le métabolisme et le rôle du facteur de croissance ou facteur "A" dans l'espèce animale et dans l'espèce humaine.

Am J Dis Child. 1934;47(4):936. doi:10.1001/archpedi.1934.01960110219021

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In this monograph Busson reports the results of his extensive studies of vitamin A in animals and in man. The biologic, colorimetric and spectroscopic methods of analysis for determining vitamin A were carefully compared, and the results showed the biologic method to be much the most reliable. Experiments with carotene demonstrated that its rôle was apparently the same as that of vitamin A of animals. Many of the common vegetables and fruits were analyzed biologically for carotene, and the results are presented in tables. Analyśis of the internal organs of animals and man showed that the liver was the chief depot for the storage of vitamin A and the regulator of vitamin A metabolism.

The use of the term "anti-infectious vitamin" is considered objectionable, since infection occurs only after the tissues have suffered great decrease in vitality and morphologic changes due to vitamin A deficiency. The "growth factor" is suggested

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