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May 1934

BLOOD CELLS IN HEALTHY YOUNG INFANTS: I. THE LEUKOCYTIC PICTURE DURING THE FIRST THREE MONTHS WITH SPECIAL REFERENCE TO HOURLY AND DAILY VARIATIONS

Author Affiliations

DENVER
From the Child Research Council and the University of Colorado School of Medicine.

Am J Dis Child. 1934;47(5):993-1010. doi:10.1001/archpedi.1934.01960120051006
Abstract

A review of the literature reveals how little accurate information exists concerning the possible variations which may be found in the leukocyte counts of a healthy infant. A brief perusal of the most modern textbooks of pediatrics shows an even greater lack of data in regard to such individual variations. The presentation of average figures for babies of a given age is not very helpful. The assumption that "average" means "normal" for a given organism is pernicious. It has been well established for a quarter of a century that the total number of leukocytes in the peripheral blood stream is subject to considerable fluctuation during the course of a few hours. This fact might well lead one to inquire how great a variation from the average may be consistent with health and what degree of fluctuation points to the presence of some disease process. An additional question is whether there

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