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Case Reports
June 1934


Author Affiliations

From the Department of Pediatrics and Infectious Disease, University of Michigan Medical School, Ann Arbor, Mich.

Am J Dis Child. 1934;47(6):1318-1322. doi:10.1001/archpedi.1934.01960130142011

Werlhof described purpura haemorrhagica in 1735, while Otto,1 in 1803, in an article called "An Account of an Hemorrhagic Disposition in Certain Families" first recorded a description of hemophilia. Since then many articles have been published to explain the differentiation of and the relationship between these two conditions, as well as to describe many atypical cases of hemorrhagic disease which cannot be grouped with either of these conditions. In 1916 Hess2 made the statement that "it is becoming increasingly evident that the group termed 'the hemorrhagic diseases' includes a large number of abnormal conditions and that, at the present time, it is a fruitless task to attempt to unravel the various entities embraced by the clinical conditions which are assembled under this general head." This unraveling process has been carried on since and is still progressing.

Hemophilia is easily diagnosed, if the condition seen is in a male