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August 1934


Author Affiliations

From the Harriet Lane Home of the Johns Hopkins Hospital and the Department of Pediatrics, Johns Hopkins University.

Am J Dis Child. 1934;48(2):309-326. doi:10.1001/archpedi.1934.01960150068005

For some years proliferative pneumonia following the aspiration of fatty material into the lung has been recognized as a pathologic entity, but never as a clinical one. It seems wise, therefore, to report the experiences of my associates and myself with lipoid cell pneumonia, because of its fairly consistent clinical picture in well marked cases, its frequency and the possibility of its prevention.

In 1885, and again two years later, Rosenberg1 reported the successful treatment of infections of the lungs by the intratracheal injection of medicated olive oil. At this time Sehrwald2 was using percutaneous tracheal puncture and injection to accomplish the same purpose, but neither of these workers mentioned pneumonia as a complication of their therapeutic procedures. The enthusiasm for intratracheal administration of antiseptics waned until Campbell3 revived the method in 1895. Although Campbell introduced as much as 20 cc. of the oil at one time

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