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October 1934

ETIOLOGY OF MONGOLISM: WITH SPECIAL REFERENCE TO ITS OCCURRENCE IN TWINS

Author Affiliations

LOS ANGELES

Am J Dis Child. 1934;48(4):764-779. doi:10.1001/archpedi.1934.01960170054004
Abstract

Cases of mongolism in twins are rather rare. We have been able to find reports of only 59 such cases in the literature. They are of special interest in that they afford an opportunity, not otherwise available, of investigating certain phases of the etiology of that condition.

In the course of a study of mental disorders in twins, undertaken over three years ago, we have collected records of 1,014 pairs of twins one or both of whom presented a mental disorder. The material is now being analyzed by clinical groups.

In our collection are included records of 5 pairs of twins with mongolism. The object of this communication is twofold: first, to report our cases, and second, to utilize this and other material in a study of the etiology of mongolism.

REPORT OF CASES  Case 1.—Monozygotic female twins, both affected.The T. twins, Florence and Frances, were born in

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