The solution of some problems in the pathology of the diseases of the respiratory tract can be approached only by the combined efforts of the internist and the bacteriologist-immunologist. Research on the relations between lobar and lobular pneumonia requires such a collaboration. It is usually considered that typical lobar pneumonia is very rare in infants and young children, occurring more frequently in older children and adults, while lobular pneumonia, on the contrary, is more frequent in infants and young children. The existence of a relation between the age of the patient and the type of pneumonia is evident, although its cause is not clear. As differences in immunity have often been thought responsible, the problem has been attacked by means of a study of immunologic reactions, i. e., cutaneous reactions, it being tacitly understood that both lobar and lobular pneumonia are caused by the pneumococcus. This is, however, not certain,
DE BRUIN M, VEDDER A. CUTANEOUS REACTIONS OF CHILDREN TO PNEUMOCOCCUS AND STREPTOCOCCUS VACCINES. Am J Dis Child. 1934;48(4):791–798. doi:10.1001/archpedi.1934.01960170081006
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