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December 1934

IODINE AND THYROID HYPERPLASIA: I. THE IODINE CONTENT OF HUMAN SKIMMED MILK FROM GOITROUS AND NONGOITROUS REGIONS

Author Affiliations

DETROIT
From the Department of Medical Research, Wayne University College of Medicine, formerly Detroit College of Medicine and Surgery.

Am J Dis Child. 1934;48(6):1209-1227. doi:10.1001/archpedi.1934.01960190029004
Abstract

R. G. TURNER, Ph.D. Assisted by Mina Z. Weeks

A systematic study of the iodine content of human milk during the period of lactation may enlighten one's course in combating or preventing thyroidhyperplasia. The following report is a step in this direction.

LITERATURE  The ideas expressed in the literature on thyroid disease are so varied and confusing that it is difficult to form a definite and concise conclusion regarding the functions and mechanism involved. Further, examination of the literature reveals little regarding the iodine content of mother's milk and its variations during the period of lactation. Most of the studies reported have been on colostrum.Maurer and Diez1 (1926) saponified colostrum with 25 per cent potassium hydroxide. After evaporation and ashing they extracted with alcohol and determined the iodine content colorimetrically after the method of von Fellenberg.2 They found that colostrum has a high iodine value with decided

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