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December 1934

PHOSPHATASE STUDIES: V. SERUM PHOSPHATASE AS A CRITERION OF THE SEVERITY AND RATE OF HEALING OF RICKETS

Am J Dis Child. 1934;48(6):1268-1278. doi:10.1001/archpedi.1934.01960190088009
Abstract

Kay1 demonstrated that plasma phosphatase was relatively high in rickets. The maximum value which he found in this condition was about seven times his average for normal children of the same age, and about eleven times his average for the normal adult.

Using our procedure for the determination of serum phosphatase,2 in which certain errors in Kay's method have been avoided, we found that serum phosphatase in rickets reached about twenty times the average for normal children and about sixty times the average for normal adults.3 We discussed some typical results, including effects of

(Footnote continued on next page) treatment with cod liver oil and viosterol, at the twenty-sixth annual meeting of the American Society of Biological Chemists in 1932,4 at the December 1933 session of the Section of Pediatrics of the New York Academy of Medicine, and in a symposium on enzymes at the Cleveland

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