Pathologic studies on acrodynia have been few. Those reported have served more and more to focus attention on the nervous system as the site of the most noteworthy pathologic changes, although a uniform and characteristic pathologic picture is still lacking. The present report gives further evidence of the neurologic nature of this syndrome.
History.—L. M., a white girl, aged 4 years, whose family history and past history were negative, during July, 1931, had an unexplained "measles-like" rash without fever which lasted a few days. One month later she became irritable and restless, did not sleep at night and had a very poor appetite. There was itching of the nose and anal region and pronounced pain in various joints and in the lower part of the back. A general maculopapular rash again appeared and the child began to perspire profusely. The mother stated that the hands had a
DEAMER WC, BISKIND GR. ACRODYNIA: REPORT OF A CASE WITH A PATHOLOGIC STUDY. Am J Dis Child. 1934;48(6):1326–1335. doi:10.1001/archpedi.1934.01960190146016
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