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February 1935

EVALUATION OF THE WHITE BLOOD CELL PICTURE IN AMBULATORY CHILDREN WITH POSITIVE TUBERCULIN REACTIONS: SUPRAVITAL STUDIES

Author Affiliations

NEW YORK
From the Department of Pediatrics, Cornell University Medical College, the New York Nursery and Child's Hospital and the New York Hospital.

Am J Dis Child. 1935;49(2):327-346. doi:10.1001/archpedi.1935.01970020042004
Abstract

The criteria for gaging activity of the tuberculous infection in the ambulatory child are difficult to evaluate. The need for an adequate appraisal of the pathologic status of the infection in a child with a positive tuberculin reaction is evident. This is particularly of moment in the child whose complaints are few, and in whom a physical examination reveals little that is abnormal.

Many laboratory procedures have been employed within recent years directed toward the determination of activity of a tuberculous focus by examination of the blood. The most common ones in use at present are the determination of the sedimentation rate of the erythrocytes, the Schilling count and the ratio of monocytes to lymphocytes. The first two indicate the changes produced by an infectious process, regardless of etiology. The last, while not entirely specific, is identified more closely than the others with the pathologic changes that take place in

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