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May 1935

ERUPTIVE FEVER WITH STOMATITIS AND OPHTHALMIA: ATYPICAL ERYTHEMA EXUDATIVUM MULTIFORME (STEVENS-JOHNSON)

Author Affiliations

NEW YORK
From the Pediatric Service of Dr. Béla Schick, Mount Sinai Hospital.

Am J Dis Child. 1935;49(5):1148-1160. doi:10.1001/archpedi.1935.01970050046003
Abstract

Stevens and Johnson1 in 1922 reported two cases of "A New Eruptive Fever Associated with Stomatitis and Ophthalmia" in children. They could find no description of a similar cutaneous eruption and thought that no known diagnosis could be made from the symptoms and course of the disease. The eruption was generalized and presented well defined characteristics. It was first noted on the back of the neck and chest, and spread to the face, arms and legs during a period of eighteen days. When they first appeared the lesions were dark red, oval macules, varying from 0.5 to 2 cm. in the longest diameter and were without areolae. Within a few days these macules became papular and brownish purple. Some of the larger lesions acquired yellow, dry, necrotic centers. Vesicles and pustules were absent. Subjective symptoms of pain or itching were strikingly absent.

There were no lesions on the scalp,

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