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May 1935


Am J Dis Child. 1935;49(5):1256-1263. doi:10.1001/archpedi.1935.01970050154016

In a previous communication1 a study of eosinophilia in scarlet fever was begun. In the present article I wish to report (1) observations on eosinophilia during the first week of illness; (2) the presence of a previously neglected phenomenon, namely, a secondary rise in the eosinophil count, and (3) the nature of the eosinophilia in scarlet fever.

METHODS AND MATERIAL  In eighty-five cases of scarlet fever, which is by far the largest series reported in the literature, eosinophil counts were made daily during the first week of illness and thereafter on alternate days (occasionally a two day interval was allowed to elapse). Blood smears were made by the slide method and stained with Wright's stain. Three hundred white cells were counted in determining the percentage of eosinophils. Only patients admitted to the hospital in an early stage of the disease, usually within a day of the appearance of the

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