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December 1935

MALDEVELOPMENT AND MALDESCENT OF THE TESTESII. FURTHER OBSERVATIONS ON TREATMENT WITH THE ANTERIOR PITUITARY-LIKE GONADOTROPIC HORMONE

Am J Dis Child. 1935;50(6):1429-1443. doi:10.1001/archpedi.1935.01970120081007
Abstract

In a previous paper1 I reported the results of treatment with anterior pituitary-like gonadotropic hormone from the urine of pregnant women in a series of fourteen boys who showed underdevelopment of the genital tract. The information which follows is based on a study of these fourteen patients. A brief review of the facts will be given and then I shall endeavor to report additional observations and deductions which I made during and after the administration of this anterior pituitary-like gonadotropic hormone from the urine of pregnant women.

Three of the patients (cases 10, 13 and 14) dropped out before treatment was completed. Two of these did not receive sufficient therapy to produce beneficial results. The third patient (case 14) received 36 cc. of the anterior pituitary growth hormone over a period of three months without the anterior pituitary-like gonadotropic hormone, but he showed no immediate response. Before treatment with

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