The discovery that more than one route may be employed in the removal of cerebrospinal fluid has given rise to the question of whether fluids removed from different loci are alike in their physical and chemical properties. At first, the question concerned itself with the comparative composition of lumbar and ventricular fluids. More recently, the frequent employment of cisternal puncture both in children and in adults has extended the problem to include a comparison of lumbar and cisternal fluid. The problem assumes a practical significance with regard to the dextrose content of the cerebrospinal fluid, which is of diagnostic value in meningitis. Namely, does the determination of the dextrose content in fluid obtained by cisternal puncture furnish information of the same value as the examination of cerebrospinal fluid obtained via the lumbar route?
Some comparative studies of lumbar and cisternal fluid have been reported in the literature. Most of these
LEVINSON A, COHN DJ. COMPARATIVE DEXTROSE CONTENT OF LUMBAR AND CISTERNAL CEREBROSPINAL FLUID. Am J Dis Child. 1936;51(1):17–29. doi:10.1001/archpedi.1936.01970130026002
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