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April 1936


Author Affiliations

From the Pediatric Department, Jewish Hospital.

Am J Dis Child. 1936;51(4):816-822. doi:10.1001/archpedi.1936.01970160054005

Instances of "infantile tetany" occurring during the first few weeks of life were reported by Kehrer1 in 1913 and by Wolff2 in 1918, but in no one of their cited cases were any data on chemical analysis of the blood given. Powers3 in 1925 and Griffith in 19264 were the first to report the concentration of calcium in the blood in children under 2 months of age who were suffering with convulsions not associated with rickets. The calcium content in both instances was 5.3 mg. per hundred cubic centimeters. No mention was made of the concentration of inorganic phosphorus or of the roentgen findings in the long bones. Since then many reports of a similar nature have appeared in the literature. Bass and Karelitz5 in 1931 and McGavran6 in 1932 reported clinically typical cases of infantile tetany occurring in the new-born, responding to calcium