Sixty-six years have elapsed since Hofmann1 in 1869 found that the excretion of creatinine varies with age, weight and sex. Although there have been numerous investigations based on the problem of creatinine and creatine, there are few data on the excretion of these in adolescence, the period during which the metabolism of creatinine and creatine may undergo the greatest change. Rose2 reported values for the creatinine and creatine excreted by adolescent girls, but his study was not made on twenty-four hour samples of urine. Light and Warren3 made an excellent study of the excretion of creatinine and creatine in adolescent boys. We have been able to find only few scattered data on that of adolescent girls between the ages of 12 and 15 years. In view of this fact, we have studied, in the course of our other metabolic investigations, the excretion of creatine and creatinine in
CHE WANG C, GENTHER I, HOGDEN C. METABOLISM OF ADOLESCENT GIRLS: III. THE EXCRETION OF CREATININE AND CREATINE. Am J Dis Child. 1936;51(6):1268–1276. doi:10.1001/archpedi.1936.01970180014002
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