Diabetes mellitus in infants and children presents problems which do not exist in a study of the disease in adults. Warren1 stated that the most characteristic pathologic change of the islands of Langerhans in diabetic children is lymphocytic infiltration. In a few cases the number and amount of island tissues are decreased. In a rare case there is apparently absence of cells which may be recognized morphologically as mature islands of Langerhans. The present report presents a case of the latter type.
REPORT OF A CASE
S. T., a 13 year old white girl born in America of Italian parents, was admitted to the New York Hospital because of pain in the side, which had been present for twenty-four hours. (Dr. Eugene DuBois supplied the clinical data.)Family History.—The father and mother were Italian-born and 44 and 35 years of age, respectively. The mother had had 6 pregnancies,
MOORE RA. CONGENITAL APLASIA OF THE ISLANDS OF LANGERHANS WITH DIABETES MELLITUS. Am J Dis Child. 1936;52(3):627–632. doi:10.1001/archpedi.1936.04140030117010
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