The fact that the insensible perspiration is altered by those factors which alter the basal metabolism suggested to Benedict and his co-workers that there must be a relationship between the two.1 Accordingly, Benedict and Root1a plotted the hourly insensible loss of weight under certain standard conditions with reference to the observed twenty-four hour heat production in the same persons, and they found a close correlation. This was later confirmed by Johnston and Newburgh,2 Jores,3 Heller and Schwarz,4 Magendantz5 and Levine and his associates.6 The last-mentioned authors showed that there is a striking correlation between heat production and insensible perspiration, whether they are measured simultaneously in a respiration chamber or independently by a Sauter balance and in a respiration chamber.
Such a correlation is possible because of the constant relationship between the total amount of heat produced and the amount lost by vaporization through
GINANDES GJ, TOPPER A. INSENSIBLE PERSPIRATION IN CHILDREN: III. STATISTICAL CORRELATION OF INSENSIBLE PERSPIRATION AND BASAL METABOLISM. Am J Dis Child. 1937;53(3):705–719. doi:10.1001/archpedi.1937.04140100035002
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