Attention has been directed in recent years to a type of dyscrasia of the blood, erythroblastosis foetalis, which occurs in the newly born. We present a case of the condition accompanied by icterus gravis neonatorum, in which what was thought to be recovery occurred after repeated blood transfusions and was followed by symptoms of degeneration of the central nervous system, which we thought were due to kernicterus. Mental retardation, muscular spasticity and convulsions were prominent, and death came when the child was 13 months old.
Diamond, Blackfan and Baty1 presented a summary of erythroblastosis foetalis, with a discussion of the pathologic process. Zimmerman and Yannet2 showed that this condition, with its concomitant jaundice, can produce kernicterus, or jaundice of the nuclear masses of the brain, which may cause the cerebral malfunctions which subsequently show themselves in patients who have had erythroblastosis foetalis. Their second paper3 definitely proves
BUSHNELL LF, ALDRICH CA. ERYTHROBLASTOSIS FOETALIS: REPORT OF A CASE IN WHICH THE PATIENT WAS TREATED AND IN WHICH THERE WERE CLINICAL SIGNS OF KERNICTERUS WITHOUT POSTMORTEM CONFIRMATION. Am J Dis Child. 1937;53(4):1053–1056. doi:10.1001/archpedi.1937.04140110123013
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